[The functional state of the sympathetic-adrenal and pituitary-adrenocortical systems during chronic neuro-emotional stress].

A study was made of the function of the sympatho-adrenal and hypophysio-adrenocortical systems by the indices of catecholamine and corticosteroid urinary excretion in the dispatchers of railway lines during the day and night, at rest and shift work associated with the nervous-emotional strain. The working activity both during the day and night produced a 1.5--3-fold increase in catecholamine and corticosteroid excretion. Night work was accompanied by disturbance of the normal circadian variations in the activity of the systems under study After work the function of the hypophyseo-adrenocortical system was restored on the second day of rest; as the the sympathico-adrenal system function--it failed to become completely normalized during the mentioned time.