Yoshida C, Endo Y, Baba Y
Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, The University of Tokushima, Shomachi, 770-8505, Tokushima, Japan.
Eur J Pharm Sci. 2001 Apr;13(1):99-103. doi: 10.1016/s0928-0987(00)00213-x.
The effect of electric field gradients are examined on the speed, selectivity, read length, and accuracy for DNA sequencing using capillary array electrophoresis. Modified electric field gradients was realized to read over 800 bases within 140 min. The method developed is effectively applicable to single nucleotide polymorphism analysis for genomic drug discovery and pharmacogenomics.
