Budzyński P, Pogoda W, Pogodziński M
Koło Naukowe III Katedry i Kliniki Chirurgii Ogólnej, Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.
Przegl Lek. 2000;57(11):611-3.
Although there is rich literature concerning seasonal fluctuations of incidence of peptic ulcer, no one can find so many data on acute complications of this disease--bleedings and perforations. There is also only little information saying about the role of meteorological factors that can take part in occurrence of the mentioned complications. This study aimed to analyze the seasonal variation (in calendar months, quarters of the year and calendar seasons--winter, spring, summer, autumn) of peptic ulcer bleeding and perforations as well as the influence of atmospheric pressure diurnal fluctuations on the occurrence of these diseases. The conducted study was retrospective and based on data of patients admitted to III Department of General Surgery of the Jagiellonian University Medical School in Cracow. Altogether, from 1993 to 1997--26 patients with peptic gastroduodenal ulcer bleeding were admitted. 220 bleedings were endoscopically proven (6 patients did not agree for gastroscopy and were excluded from further analysis). 157 patients were treated because of peptic ulcer perforation at the same time and all of them underwent surgical procedure during which perforation was proven. The chi 2 test was used in order to verify our statistic hypothesis (p = 0.05). The examination did not show any significant seasonal variation of the studied complications. Neither hemorrhage nor perforation presented any seasonal prevalence. As for calendar months, quarters and calendar seasons (p > 0.01; p > 0.02; p > 0.02 respectively). However, the study confirmed the role of atmospheric pressure falls in the occurrence of both: bleeding and perforation of peptic ulcer (p < 0.001). 153 patients with bleeding were admitted on days with decreasing pressure, while 67 when pressure was going up. Similarly as for perforations--94 with falling down to 33 with growing up pressure.
尽管有大量关于消化性溃疡发病率季节性波动的文献，但没有人能找到如此多关于该疾病急性并发症——出血和穿孔的数据。关于气象因素在上述并发症发生中可能起的作用，也只有很少的信息。本研究旨在分析消化性溃疡出血和穿孔的季节性变化（按日历月、一年中的季度以及日历季节——冬季、春季、夏季、秋季），以及大气压力日波动对这些疾病发生的影响。所进行的研究是回顾性的，基于克拉科夫雅盖隆大学医学院普通外科第三科室收治患者的数据。1993年至1997年期间，共有26例患有消化性胃十二指肠溃疡出血的患者入院。220次出血经内镜证实（6例患者不同意进行胃镜检查，被排除在进一步分析之外）。同时，有157例患者因消化性溃疡穿孔接受治疗，他们均接受了手术，术中证实了穿孔情况。使用卡方检验来验证我们的统计假设（p = 0.05）。检查未显示所研究并发症有任何显著的季节性变化。出血和穿孔均未表现出任何季节性高发。就日历月、季度和日历季节而言（分别为p > 0.01；p > 0.02；p > 0.02）。然而，该研究证实了大气压力下降在消化性溃疡出血和穿孔发生中的作用（p < 0.001）。153例出血患者在压力下降的日子入院，而压力上升时为67例。穿孔情况类似——压力下降时有94例，压力上升时有33例。
