Lagorio S, Forastiere F, Lipsett M, Menichini E
Laboratorio di Igiene Ambientale, Istituto Superiore di Sanità, Roma.
Ann Ist Super Sanita. 2000;36(3):311-29.
This paper describes the epidemiological evidence on lung cancer and childhood leukemia in relation to traffic-related air pollution, with particular reference to diesel exhausts, polycyclic aromatic hydrocarbons (PAH) and benzene. Recent epidemiological studies strengthen the hypothesis of an increased lung cancer risk related to residential exposure to air pollution and to occupational exposure to diesel exhausts. The evidence on the carcinogenicity of several PAH mixtures comes from occupational studies, while the risk incurred by the general population is difficult to estimate. A few papers suggest that traffic-related air pollution may be associated with an increased risk of childhood leukemia. The observed relative risks are small but the exposure is widespread. Therefore, the overall impact of exposure to current levels of urban air pollution may be substantial.
本文描述了与交通相关的空气污染，尤其是柴油废气、多环芳烃（PAH）和苯与肺癌及儿童白血病相关的流行病学证据。近期的流行病学研究强化了这样一种假说，即居住环境暴露于空气污染以及职业性暴露于柴油废气会增加患肺癌的风险。关于几种多环芳烃混合物致癌性的证据来自职业研究，而普通人群所面临的风险则难以估计。有几篇论文表明，与交通相关的空气污染可能与儿童白血病风险增加有关。观察到的相对风险较小，但暴露情况广泛。因此，暴露于当前城市空气污染水平的总体影响可能很大。
