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精神分裂症为何在青春期后期发病?

Why does schizophrenia develop at late adolescence?

作者信息

Harrop C, Trower P

机构信息

School of Psychology, University of Birmingham, Edgbaston, Birmingham, B15 2TT, England.

出版信息

Clin Psychol Rev. 2001 Mar;21(2):241-65. doi: 10.1016/s0272-7358(99)00047-1.

DOI:10.1016/s0272-7358(99)00047-1
PMID:11293367
Abstract

Schizophrenia is one of the most researched, yet still one of the least understood, of the mental disorders. One key area that remains comparatively neglected is the fact that schizophrenia typically develops at late adolescence. In common with people with psychotic disorders, around 25% of normal teenagers also report finding adolescence very distressing, and a substantial empirical literature shows that certain characteristics typical of adolescence such as conflicted family relationships, grandiosity, egocentrism, and magical ideation bear a distinct resemblance to phenomena seen in psychotic disorders. Indeed, such phenomena, as might be judged prodromal or symptomatic in first-onset schizophrenia, have been shown to be remarkably common in normal adolescents, generally in about 50% of samples. Furthermore, prodromal-like signs in normal adolescents appear to be functionally linked to psychological development. For most adolescents, such phenomena pass with successful psychological development. It is proposed that psychosis in late adolescence is a consequence of severe disruption in this normally difficult psychological maturational process in vulnerable individuals, and explanations are offered as to why and how this comes about. It is suggested that problems either in reaching psychological maturity with regard to parents or in bonding to peers or both, may lead to crucial self-construction difficulties, and that psychosis emerges out of such "blocked adolescence." This approach proposes therapeutic interventions that enable professional services to side with both parents and clients simultaneously, and is normalizing and stigma-free.

摘要

精神分裂症是研究最多但仍最不为人所理解的精神障碍之一。一个相对被忽视的关键领域是,精神分裂症通常在青春期后期发病。与患有精神障碍的人一样,约25%的正常青少年也表示青春期非常痛苦,大量实证文献表明,青春期的某些典型特征,如冲突的家庭关系、夸大、自我中心和奇幻思维,与精神障碍中出现的现象有明显相似之处。事实上,这些在首次发作精神分裂症中可能被判断为前驱或症状性的现象,在正常青少年中非常常见,通常在约50%的样本中出现。此外,正常青少年中的前驱样症状似乎与心理发展存在功能联系。对大多数青少年来说,这些现象会随着心理的成功发展而消失。有人提出,青春期后期的精神病是脆弱个体在这个通常艰难的心理成熟过程中严重紊乱的结果,并对其发生的原因和方式进行了解释。有人认为,在与父母达成心理成熟或与同龄人建立联系或两者兼而有之方面出现的问题,可能会导致关键的自我建构困难,而精神病则产生于这种“受阻的青春期”。这种方法提出了治疗干预措施,使专业服务能够同时支持父母和患者,并且是正常化且无污名化的。

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Why does schizophrenia develop at late adolescence?精神分裂症为何在青春期后期发病?
Clin Psychol Rev. 2001 Mar;21(2):241-65. doi: 10.1016/s0272-7358(99)00047-1.
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