Hans S L, Auerbach J G, Asarnow J R, Styr B, Marcus J
Department of Psychiatry, The University of Chicago, IL 60637, USA.
J Am Acad Child Adolesc Psychiatry. 2000 Nov;39(11):1406-14. doi: 10.1097/00004583-200011000-00015.
To better understand whether poor social adjustment, a core characteristic of schizophrenic illness, may also be an indicator of vulnerability in young people who are at genetic risk for schizophrenia, but who do not have schizophrenia.
Between 1992 and 1996, 27 Israeli adolescents with a schizophrenic parent, 29 adolescents with no mentally ill parent, and 30 adolescents with a parent having a nonschizophrenic mental disorder were assessed on multiple domains of social adjustment measured using the Social Adjustment Inventory for Children and Adolescents and the Youth Self-Report.
Young people with a schizophrenic parent showed poor peer engagement, particularly heterosexual engagement, and social problems characterized by immaturity and unpopularity with peers. These social adjustment difficulties in youths at risk for schizophrenia could not be attributed solely to the presence of early-onset mental disorders, although problems were greater in those with disorders in the schizophrenia spectrum. Young people whose parents had other disorders showed different patterns of social maladjustment characterized by difficult, conflictual relationships with peers and family.
Adolescents at risk for schizophrenia have social deficits that extend beyond early-onset psychopathology and that may reflect vulnerability to schizophrenic disorder.
为了更好地了解社交适应不良这一精神分裂症疾病的核心特征，是否也可能是有精神分裂症遗传风险但尚未患精神分裂症的年轻人易感性的一个指标。
在1992年至1996年期间，对27名有精神分裂症父母的以色列青少年、29名无精神疾病父母的青少年以及30名父母患有非精神分裂症精神障碍的青少年，使用儿童和青少年社会适应量表以及青少年自我报告，在社交适应的多个领域进行了评估。
有精神分裂症父母的年轻人表现出同伴交往不佳，尤其是异性交往方面，以及以不成熟和不受同伴欢迎为特征的社交问题。有精神分裂症风险的年轻人的这些社会适应困难不能仅仅归因于早发性精神障碍的存在，尽管精神分裂症谱系障碍患者的问题更为严重。父母患有其他疾病的年轻人表现出不同的社会适应不良模式，其特征是与同伴和家人关系困难、冲突。
有精神分裂症风险的青少年存在社交缺陷，这些缺陷超出了早发性精神病理学范畴，可能反映了对精神分裂症的易感性。
