Shukla-Dave A, Gupta R K, Roy R, Husain N, Paul L, Venkatesh S K, Rashid M R, Chhabra D K, Husain M
Department of Radiology, Sanjay Gandhi Post-Graduate Institute of Medical Sciences, Lucknow 226014, India.
Magn Reson Imaging. 2001 Jan;19(1):103-10. doi: 10.1016/s0730-725x(01)00224-7.
Proton MR spectroscopy (PMRS) has been found to be useful in differentiating various cystic intracranial lesions. The purpose of the present study was to prospectively evaluate the spectral pattern of various cystic lesions of brain with similar imaging appearances and to determine the accuracy of this technique in the differential diagnosis of these lesions. Fifty-one patients with intracranial cystic lesions (21 abscesses, 20 gliomas, 3 hydatid cysts, 3 arachnoid cysts, 1 case each of glioependymal cyst, xanthogranuloma, infarction and acoustic neuroma) were evaluated with conventional MR imaging and in vivo PMRS. Ex vivo PMRS of the cystic contents aspirated at surgery in 31 cases was also done to confirm the in-vivo results. Preoperative diagnosis of the lesions was based on the results of in vivo PMRS. In vivo PMRS accurately predicted the pathology in 92% of the cases. We conclude that in-vivo PMRS complements imaging in better characterization of cystic intracranial mass lesions.
质子磁共振波谱（PMRS）已被证明在鉴别各种颅内囊性病变方面很有用。本研究的目的是前瞻性评估具有相似影像学表现的各种脑囊性病变的波谱模式，并确定该技术在这些病变鉴别诊断中的准确性。对51例颅内囊性病变患者（21例脓肿、20例胶质瘤、3例包虫囊肿、3例蛛网膜囊肿、各1例胶质室管膜囊肿、黄色肉芽肿、梗死和听神经瘤）进行了常规磁共振成像和活体PMRS评估。还对31例手术中吸出的囊性内容物进行了离体PMRS检查，以证实活体检查结果。病变的术前诊断基于活体PMRS的结果。活体PMRS在92%的病例中准确预测了病理结果。我们得出结论，活体PMRS有助于更好地鉴别颅内囊性占位性病变，对影像学检查起到补充作用。
