Raz R
Infectious Diseases Unit, Haemek Medical Center, Afula 18101, Israel.
Int J Antimicrob Agents. 2001 Apr;17(4):269-71. doi: 10.1016/s0924-8579(00)00355-1.
Urinary tract infection is a frequent disease in elderly women. The lack of estrogen, which characterizes the postmenopause, plays an important role in the pathogenesis of this infective disease. Exogenous estrogen replacement, however, is very effective in the prevention of bacteriuria in these women. The safety of oral and vaginal estriol and their efficacy in comparison to antimicrobial prophylaxis should be confirmed in the future.
尿路感染是老年女性的常见疾病。绝经后雌激素缺乏是其特征，在这种感染性疾病的发病机制中起重要作用。然而，外源性雌激素替代疗法在预防这些女性的菌尿方面非常有效。口服和阴道用雌三醇的安全性及其与抗菌预防相比的疗效，未来应予以证实。
