Dontsova G V
Sov J Dev Biol. 1975 Jul;5(4):364-7.
The amount of mitochondrial DNA and its synthesis were investigated in quail oocytes during the last 20 days of their growth. As the oocyte grows the amount of DNA in it increases rapidly, but at the end of oogenesis the increase in the amount of DNA lags considerably behind the rate of increase in the volume of the oocyte. As the oocyte grows the incorporation of H-3-thymidine into mitochondrial DNA decreases. The synthesis of mitochondrial DNA in cells of the quail embryo in early stages of development takes place at the same rate as the synthesis of nuclear DNA and far more rapidly than is more inhibited by ethidium bromide and mitomycin than the synthesis of nuclear DNA.
对鹌鹑卵母细胞生长最后20天期间的线粒体DNA数量及其合成进行了研究。随着卵母细胞的生长，其中的DNA数量迅速增加，但在卵子发生结束时，DNA数量的增加远远落后于卵母细胞体积的增加速度。随着卵母细胞的生长，H-3-胸腺嘧啶核苷掺入线粒体DNA的量减少。鹌鹑胚胎发育早期细胞中线粒体DNA的合成速度与核DNA的合成速度相同，且比核DNA的合成速度快得多，溴化乙锭和丝裂霉素对其抑制作用比对核DNA合成的抑制作用更大。
