[有无术前用药的插管操作对昏迷性颅内出血的影响]

[Influence of intubation maneuver with or without premedication for intracranial hemorrhage with unconsciousness].

作者信息

Yanagawa Y, Sakamoto T, Okada Y, Tsuzuki N, Katoh H, Nawashiro H, Shima K

机构信息

Departments of Traumatology and Critical Care Medicine, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.

出版信息

No To Shinkei. 2001 Mar;53(3):247-51.

PMID:11296398

Abstract

PURPOSE

To clarify the influence of intubation maneuver with or without premedication for intracranial hemorrhage with unconsciousness.

METHODS

Between May 1995 and May 2000, we analyzed retrospectively 46 patients who had received intubation for unconsciousness and were found non-traumatic intracranial hemorrhage by head computer tomography at the Trauma and Critical Care Center, National Defense Medical College. They were divided into two groups, Drug group in which drugs were used before intubation and Control group which were intubated without drugs. Physical findings on admission, head CT findings, Glasgow Outcome Score(GOS) at discharge were analyzed between the groups.

RESULTS

There were no significant differences for background of subjects between the groups. In the Drug group, diazepam, pentazocine, lidocaine, nifedipine and nicardipine were used before intubation. GOS in the Control group was significantly greater than in the Drug group(p < 0.01).

CONCLUSION

In case of intubation for unconscious patients who may suffer intracranial hemorrhage, using premedication leads to favorable outcome.

摘要

目的

阐明有无术前用药的插管操作对伴有意识障碍的颅内出血的影响。

方法

1995年5月至2000年5月间，我们对国防医学院创伤与重症监护中心46例因意识障碍接受插管且经头颅计算机断层扫描发现为非创伤性颅内出血的患者进行了回顾性分析。他们被分为两组，插管前用药的药物组和未用药插管的对照组。分析了两组患者的入院体格检查结果、头颅CT检查结果、出院时的格拉斯哥预后评分（GOS）。