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[纹状体和海马体损伤大鼠的内时间估计和情绪行为受损]

[Impairement of estimation of the inner time and the emotional behavior in rats with the lesioned striatum and hippocampus].

作者信息

Vodolazhskaia M G, Beĭer E V

机构信息

Stavropol State University, Russia, 355009, Stavropol, Pushkin St., 1, and Stavropol State Medical Academy, Russia, 355000, Stavropol, Mira St., 310.

出版信息

Ross Fiziol Zh Im I M Sechenova. 2001 Feb;87(2):170-81.

Abstract

Bilateral lesion of the striatum delayed time conditioning in rats, induced anxiety, rearranged normal correlation between the anxiety level and autochronometrical ability. These shifts progressed along with an augmentation of the striatum lesion extent. Combined striat- and hippocampectomy as well as the latter alone resulted in a complete absence of time counting learning irrespective of the brain lesion extent. In these animals anxiety was also more obvious.

摘要

纹状体双侧损伤会延迟大鼠的时间条件反射,引发焦虑,改变焦虑水平与自计时能力之间的正常关联。这些变化随着纹状体损伤范围的扩大而进展。纹状体和海马联合切除以及单独切除海马,无论脑损伤程度如何,都会导致完全无法进行时间计数学习。在这些动物中,焦虑也更为明显。

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