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一种用于测量效用的具备互联网功能的计算机程序的可靠性和内部一致性。

The reliability and internal consistency of an Internet-capable computer program for measuring utilities.

作者信息

Lenert L A

机构信息

Section on Health Services Research, Veterans Affairs Medical Center, San Diego, CA 92161, USA.

出版信息

Qual Life Res. 2000;9(7):811-7. doi: 10.1023/a:1008933720016.

Abstract

OBJECTIVE

The purpose of this study was to assess the reliability and internal consistency of measurements of utilities performed with a computer program (iMPACT2) designed for Internet surveys and Internet patient decision-support systems.

METHODS

We implemented the Internet Multimedia Preference Assessor Construction Tool, version 2 (iMPACT2) program using the combination of a web server, HTML files, and a web-accessible database. The program randomized subjects, screened their responses for missing data and failures of internal consistency, assisted patients with resolving certain inconsistencies, and, upon a subject's completion of the protocol, provided a report of results to the research assistant administering the program. To validate the iMPACT2 program, we recruited 60 healthy community volunteers and elicited preferences in a research-lab setting using a visual analog scale (VAS) and the standard gamble (SG) for subject's current health and three hypothetical states. For purposes of comparison, we also administered a Short Form-12 (SF-12) health-assessment questionnaire. Subjects used the computer software on two occasions separated by 2-4 weeks of time.

RESULTS

Visual analog scale and standard gamble ratings for subjects' current health were reliable (intraclass correlation coefficient (ICC) of 0.82 and 0.84 (two outliers excluded -0.60 without exclusions), respectively) were comparable with the reliability of the Physical and Mental Component scales of the SF-12 (ICCs of 0.84 and 0.75, respectively). Subjects could easily discriminate between hypothetical states (D scores 0.74 for SG and 0.90 for VAS), and 94% had a completely internally consistent ordering of preference ratings for states.

CONCLUSIONS

iMPACT2 produces measurements of standard gamble utilities that are reliable and have a high degree of internal consistency. Procedures for assessment of utilities developed for desktop computer programs can be translated to software designed for the Internet, facilitating the use of utilities and endpoints in clinical trials and development of web-based decision-support applications for patients. However, further testing, including direct comparisons with traditional interviewer administered utility elicitation protocols, is needed.

摘要

目的

本研究旨在评估一款为互联网调查和互联网患者决策支持系统设计的计算机程序(iMPACT2)所进行的效用测量的可靠性和内部一致性。

方法

我们通过结合网络服务器、HTML文件和可通过网络访问的数据库来实施互联网多媒体偏好评估构建工具第2版(iMPACT2)程序。该程序对受试者进行随机分组,筛查他们的回答以查找缺失数据和内部一致性失败情况,协助患者解决某些不一致问题,并在受试者完成方案后,向管理该程序的研究助理提供结果报告。为验证iMPACT2程序,我们招募了60名健康的社区志愿者,并在研究实验室环境中使用视觉模拟量表(VAS)和标准博弈法(SG)来获取他们对当前健康状况以及三种假设状态的偏好。为作比较,我们还发放了一份简短健康调查问卷12项版本(SF - 12)。受试者在相隔2 - 4周的两个时间点使用该计算机软件。

结果

受试者当前健康状况的视觉模拟量表和标准博弈法评分是可靠的(组内相关系数(ICC)分别为0.82和0.84(排除两个异常值后 - 未排除时为0.60)),与SF - 12的身体和心理成分量表的可靠性相当(ICC分别为0.84和0.75)。受试者能够轻松区分假设状态(SG的D分数为0.74,VAS的D分数为0.90),并且94%的受试者对状态的偏好评分具有完全内部一致的排序。

结论

iMPACT2所产生的标准博弈效用测量是可靠的,并且具有高度的内部一致性。为桌面计算机程序开发的效用评估程序可以转化为针对互联网设计的软件,这有助于在临床试验中使用效用和终点指标,并为患者开发基于网络的决策支持应用程序。然而,还需要进一步测试,包括与传统的由访谈者实施的效用诱导方案进行直接比较。

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