Pérez-Losada E, Pujol R M, Domingo P, Matias-Guiu X, Lenti J, López-Pousa A, Alomar A
Department of Dermatology, Hospital de la Santa Creu i Sant Pau. Hospital del Mar, IMAS, Barcelona, Spain.
Clin Exp Dermatol. 2001 Mar;26(2):182-3. doi: 10.1046/j.1365-2230.2001.00791.x.
A 62-year-old woman with acquired hypertrichosis lanuginosa as a paraneoplastic presenting sign of an extraskeletal Ewing's sarcoma is described. Despite initial comprehensive screening to rule out an associated malignancy, a definitive diagnosis of sarcoma was established only 1 year after the onset of the cutaneous symptoms. To the best of our knowledge, this is the first report of hypertrichosis lanuginosa acquisita associated with a soft tissue sarcoma. Our observation expands the spectrum of malignancies associated with this uncommon paraneoplastic disorder.
