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加强临床研究流程:新世纪的培训方法。

Enhancing the clinical research pipeline: training approaches for a new century.

作者信息

Moskowitz J, Thompson J N

机构信息

Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1023, USA.

出版信息

Acad Med. 2001 Apr;76(4):307-15. doi: 10.1097/00001888-200104000-00004.

DOI:10.1097/00001888-200104000-00004
PMID:11299141
Abstract

There is growing concern that the numbers of physician-scientists being trained in U.S. academic health centers will not be sufficient to continue the rate of current progress in biomedical research. The authors believe that the needs of current trainees and junior faculty must be addressed immediately, and that programs to train the next generation of patient-oriented researchers must be established without delay. The authors describe a two-pronged approach to this looming crisis. First is a description of innovative educational programs implemented at one academic health center from the K-12 level through the medical-school curriculum. Second, programs are discussed that have been developed to facilitate the recruitment, training, and retention of physician-scientists in the early parts of their professional careers. Four models of training "translational" investigators are presented, along with case studies of how these models have been implemented in real-life productive and professionally satisfying collaborations within one academic health center. The authors conclude by stating that to be prepared for the effects of future knowledge on human disease and preventive health, academic health centers must enhance training opportunities for physician-scientists.

摘要

人们越来越担心,在美国学术健康中心接受培训的医师科学家数量将不足以维持生物医学研究目前的进展速度。作者认为,必须立即满足当前学员和初级教员的需求,并且必须毫不拖延地建立培训下一代以患者为导向的研究人员的项目。作者描述了应对这一迫在眉睫危机的双管齐下方法。首先是对在一个学术健康中心从幼儿园到12年级水平直至医学院课程所实施的创新教育项目的描述。其次,讨论了为促进医师科学家在其职业生涯早期的招聘、培训和留用而制定的项目。介绍了四种培训“转化型”研究人员的模式,以及这些模式如何在一个学术健康中心内实际的富有成效且令人满意的专业合作中得以实施的案例研究。作者最后指出,为应对未来知识对人类疾病和预防健康的影响做好准备,学术健康中心必须增加医师科学家的培训机会。

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