Bradley Ryan, Booth-LaForce Cathryn, Hanes Doug, Scott Craig, Sherman Karen J, Lin Yvonne S, Zwickey Heather
1 Helfgott Research Institute, National University of Natural Medicine, Portland, OR.
2 Department of Pharmaceutics, University of Washington, Seattle, WA.
J Altern Complement Med. 2019 May;25(5):509-516. doi: 10.1089/acm.2018.0454. Epub 2019 Feb 12.
Despite wide use by the public, limited evidence is available for many complementary and integrative health (CIH) practices. Thus, clinical researchers knowledgeable about CIH disciplines are necessary to study the efficacy and effectiveness of CIH practices to benefit the public health. To partially address the need for clinical researchers versed in CIH, the authors of this study report the design of an interprofessional clinical research training program focused on CIH, the Building Research across Interdisciplinary Gaps (BRIDG) program, supported by a 5-year T90/R90 grant from the National Center for Complementary and Integrative Health. The T90-supported arm of the program trains doctoral-level CIH providers in clinical research at the research-intensive University of Washington. The R90-supported arm of the program trains researchers with conventional backgrounds in the practices of CIH at the clinic-intensive National University of Natural Medicine. The "Translational Science Spectrum" provides a common conceptual framework for both programs. Specific program elements include: individualized didactic training in clinical research and CIH disciplines; placement with clinical research mentors; placement with clinical mentors in CIH disciplines; shared and independent research project development; and interdisciplinary experiences through seminars and retreats. Program evaluation includes annual completion of the Clinical Research Appraisal Inventory (CRAI), which queries confidence in research skills and methods and periodic evaluation of training elements using the Supplemental Kellogg Logic-World Health Organization model, which emphasizes relevance, adequacy, efficiency, effectiveness, process, impact, equity, and sustainability. The BRIDG program exemplifies a new standard in interprofessional clinical research training, made possible through strong collaboration between disparate research- and clinically intensive institutions.
尽管公众广泛使用多种补充和整合健康(CIH)方法,但关于这些方法的证据有限。因此,需要有CIH学科知识的临床研究人员来研究CIH方法的疗效和效果,以促进公众健康。为了部分满足对精通CIH的临床研究人员的需求,本研究的作者报告了一项跨专业临床研究培训项目的设计,即跨学科差距构建研究(BRIDG)项目,该项目由国家补充和整合健康中心提供的为期5年的T90/R90资助。该项目中由T90资助的部分在研究密集型的华盛顿大学培训博士水平的CIH从业者进行临床研究。该项目中由R90资助的部分在临床密集型的国立自然医学院培训具有传统背景的研究人员掌握CIH方法。“转化科学光谱”为这两个项目提供了一个共同的概念框架。具体的项目内容包括:临床研究和CIH学科的个性化教学培训;与临床研究导师一起实习;与CIH学科的临床导师一起实习;共同和独立的研究项目开发;以及通过研讨会和务虚会获得跨学科经验。项目评估包括每年完成临床研究评估量表(CRAI),该量表询问对研究技能和方法的信心,并使用补充的凯洛格逻辑 - 世界卫生组织模型对培训内容进行定期评估,该模型强调相关性、充分性、效率、有效性、过程、影响、公平性和可持续性。BRIDG项目体现了跨专业临床研究培训的新标准,这通过不同的研究型和临床密集型机构之间的紧密合作得以实现。