Rizo B, Dimitrov D, Bodurov N, Elezov G
Vet Med Nauki. 1975;12(2):23-30.
Comparative experimental studies on female dogs and rabbits revealed the extent to which the penetration and deposition of streptomycin in the tissues of the uterus, oviducts, mesometrium, ovaries, the blood serum and other organs take place. The antibiotic is applied i/m, via the uterus through electrohoresis following a method developed by the authors and through simple introduction into the uterus. Results have shown that the electrophoretic introduction of streptomycin is advantageous in terms of a readily achieved depot in the tissues mentioned above which remains active at values above the therapeutic concentrations 24 to 48 hours following the application of the antibiotic.
对雌性犬和兔的对比实验研究揭示了链霉素在子宫、输卵管、子宫系膜、卵巢、血清及其他器官组织中的渗透和沉积程度。抗生素通过肌肉注射、按照作者研发的方法经子宫进行电泳以及直接注入子宫等方式给药。结果表明,就链霉素在上述组织中易于形成储存库而言,电泳给药具有优势,在应用抗生素后24至48小时内,该储存库在高于治疗浓度的水平下仍保持活性。