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脑瘫患儿的癫痫

Epilepsy in children with cerebral palsy.

作者信息

Bruck I, Antoniuk S A, Spessatto A, Bem R S, Hausberger R, Pacheco C G

机构信息

Center of Pediatric Neurology, Pediatric Department, Clinical Hospital, Federal University of Parana.

出版信息

Arq Neuropsiquiatr. 2001 Mar;59(1):35-9. doi: 10.1590/s0004-282x2001000100008.

Abstract

OBJECTIVE

To describe the prevalence and characteristics of epilepsy in patients with cerebral palsy in a tertiary center.

METHODS

a total of 100 consecutive patients with cerebral palsy were retrospectively studied. Criteria for inclusion were follow-up period for at least 2 years. Types and incidence of epilepsy were correlated with the different forms of cerebral palsy. Other factors associated with epilepsy such as age of first seizure, neonatal seizures and family history of epilepsy were also analysed.

RESULTS

follow-up ranged between 24 and 151 months (mean 57 months). The overall prevalence of epilepsy was 62%. Incidence of epilepsy was predominant in patients with hemiplegic and tetraplegic palsies: 70.6% and 66.1%, respectively. First seizure occurred during the first year of life in 74.2% of patients with epilepsy. Generalized and partial were the predominant types of epilepsy (61.3% and 27.4%, respectively). Thirty-three (53.2%) of 62 patients were seizure free for at least 1 year. Neonatal seizures and family history of epilepsy were associated with a higher incidence of epilepsy.

CONCLUSIONS

epilepsy in cerebral palsy can be predicted if seizures occur in the first year of life, in neonatal period and if there is family history of epilepsy.

摘要

目的

描述在一家三级医疗中心脑瘫患者中癫痫的患病率及特征。

方法

对100例连续的脑瘫患者进行回顾性研究。纳入标准为随访期至少2年。癫痫的类型及发病率与不同形式的脑瘫相关。还分析了与癫痫相关的其他因素,如首次发作年龄、新生儿惊厥及癫痫家族史。

结果

随访时间为24至151个月(平均57个月)。癫痫的总体患病率为62%。癫痫发病率在偏瘫和四肢瘫患者中占主导:分别为70.6%和66.1%。74.2%的癫痫患者首次发作发生在生命的第一年。全身性和部分性癫痫是主要类型(分别为61.3%和27.4%)。62例患者中有33例(53.2%)至少1年无癫痫发作。新生儿惊厥和癫痫家族史与癫痫的较高发病率相关。

结论

如果在生命的第一年、新生儿期出现癫痫发作以及存在癫痫家族史,脑瘫患者的癫痫是可以预测的。

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