Antoniuk S A, Oliva L V, Bruck I, Malucelli M, Yabumoto S, Castellano J L
Centro de Neuropediatria, Departamento de Pediatria, Hospital de Clínicas, Universidade Federal do Paraná, Brazil.
Arq Neuropsiquiatr. 2001 Mar;59(1):40-5. doi: 10.1590/s0004-282x2001000100009.
Sudden unexpected, unexplained death in epilepsy (SUDEP) has been reported to be responsible for 2 to 17% of all deaths in patients with epilepsy. This study was conducted to determine the circumstances of SUDEP and the autopsy findings in these patients. Fifty-three individuals whose cause of death was related to epilepsy were identified and in 30 cases relatives or friends were interviewed about the circumstances of death and other information which allowed to classify the patients as SUDEP or not. The death certificates were also reviewed. We found 20 cases of SUDEP. Most of them were found dead lying on the bed with no evidence of seizure event, and most of them had pulmonary and/or cerebral edema as the cause of death. The incidence and the risk of SUDEP can only be fully ascertained if all sudden deaths had postmortem examination. Consensus in certifying SUDEP cases would allow better accuracy in national mortality rate.
据报道，癫痫猝死（SUDEP）占癫痫患者死亡总数的2%至17%。本研究旨在确定SUDEP的发生情况以及这些患者的尸检结果。确定了53例死因与癫痫相关的个体，并对其中30例患者的亲属或朋友就死亡情况及其他信息进行了访谈，以便将患者分类为是否为SUDEP。同时也对死亡证明进行了审查。我们发现了20例SUDEP病例。其中大多数被发现死在床上，没有癫痫发作的证据，且大多数死于肺水肿和/或脑水肿。只有对所有猝死病例进行尸检，才能全面确定SUDEP的发病率和风险。在认证SUDEP病例方面达成共识将提高国家死亡率数据的准确性。
