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[哥伦比亚东部酷似肌营养不良症的慢性重症肌无力]

[Chronic myasthenia gravis mimicking muscular dystrophy, in eastern Colombia].

作者信息

León-S F E, Cotes De A F

机构信息

Neurología Clínica Neurociencias Aplicada; Universidad Industrial de Santander MD, PhD, Bucaramanga, Colombia.

出版信息

Rev Neurol. 2001;32(2):145-7.

Abstract

INTRODUCTION. Myasthenia gravis is an apparently well-defined neuromuscular disease with some variants, including one recently described as chronic myasthenia gravis. CASE REPORT. We present a 22 year old Columbian woman who complained of progressive weakness for the previous four years, affecting her pelvic and shoulder girdles but with no clinical involvement of the extra-ocular muscles. Repetitive stimulation of the neuro-muscular junction of the abductor digiti quinti muscle was negative, but positive for myasthenia gravis in the trapezius muscle and the right orbital eye muscles. Her symptoms improved and the clinical neurophysiological studies were normal again after treatment with pyridostigimine, which confirmed the diagnosis.

摘要

引言。重症肌无力是一种明显界定明确的神经肌肉疾病,存在一些变体,包括一种最近被描述为慢性重症肌无力的类型。病例报告。我们报告一名22岁的哥伦比亚女性,她主诉在过去四年中逐渐出现肌无力,累及骨盆带和肩胛带,但眼外肌无临床受累。对小指展肌神经肌肉接头进行重复刺激结果为阴性,但斜方肌和右眼眼肌的重症肌无力检查结果为阳性。使用吡啶斯的明治疗后,她的症状有所改善,临床神经生理学研究结果再次恢复正常,这证实了诊断。

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