Papp L, Kosztyu L, Kanyári Z
Debreceni Orvostudományi Egyetem I. sz. Sebészeti Klinika.
Magy Seb. 2001 Feb;54(1):32-40.
Arterial thrombolysis is a well established treatment for acute myocardial ischaemia, with respectable results. It is gaining ground in peripheral vascular surgery as well, particularly in the treatment of acute ischaemia due to occlusion of a sclerotic artery or an arterial graft. However, in case of myocardial ischaemia diagnosis (coronary angiogram), treatment (thrombolysis, PTCA or revascularisation) and recognition for the need for acute surgical treatment are in the same hands in cardiology, in case of peripheral arterial occlusions diagnostics (and therapy in some extent) are provided by radiologists, while patients are usually referred to vascular surgeons. They can provide limited diagnostics (intraoperative angiogram) and can treat patients by non-surgical means (i.e. intraoperative thrombolysis). Although co-operation between radiology and vascular surgical services is crucial and can save limbs and lives, in everyday practice we frequently have to decide whether the ischaemic limb can be treated by thrombolysis only (carried out by radiologists) or the extent and stage of ischaemia are such that they require the faster surgical reconstruction, often completed with intraoperative angiogram and thrombolysis. Whose decision should it be? Should vascular surgeons force thrombolysis, should they do it themselves? What are the cost implications of the successful and unsuccessful thrombolysis?
动脉溶栓是治疗急性心肌缺血的一种成熟疗法,效果显著。它在外周血管外科领域也越来越受到重视,特别是在治疗因硬化动脉或动脉移植物闭塞导致的急性缺血方面。然而,在心肌缺血的诊断(冠状动脉造影)、治疗(溶栓、经皮冠状动脉腔内血管成形术或血运重建)以及确定是否需要急性手术治疗方面,心脏病学领域都由同一批人负责;而在外周动脉闭塞的情况下,诊断(在一定程度上也包括治疗)由放射科医生提供,患者通常会被转诊至血管外科医生处。血管外科医生可以提供有限的诊断(术中血管造影),并能通过非手术手段(如术中溶栓)治疗患者。尽管放射科和血管外科服务之间的合作至关重要,能够挽救肢体和生命,但在日常实践中,我们常常需要决定缺血肢体是否仅能通过溶栓治疗(由放射科医生进行),或者缺血的程度和阶段是否需要更快地进行手术重建,这种重建通常会结合术中血管造影和溶栓。应该由谁来做这个决定呢?血管外科医生应该强制进行溶栓治疗吗?他们自己来做吗?溶栓成功和失败的成本影响是什么?