Shiriĭ A V
Vopr Onkol. 1975;21(3):35-40.
The reaction of blast-transformation of peripheral blood lymphocytes was studied in 60 patients with cervical cancer depending on a stage and radiotherapy applied. A progression of the tumor process reduces the capacity of peripheral blood lymphocytes for blasttransformation in the FHA stimulated culture. The conducted radiotherapy would enhance a suppression of functional properties of T-lymphocytes. The use of the blasttransformation reaction seems to be possible for estimation of changes in the cellular immunity in oncological patients during radiotherapy.
根据宫颈癌分期和放疗情况,对60例宫颈癌患者外周血淋巴细胞的 blast 转化反应进行了研究。肿瘤进程的进展会降低外周血淋巴细胞在FHA刺激培养物中的 blast 转化能力。进行的放疗会增强对T淋巴细胞功能特性的抑制。blast 转化反应的应用似乎可用于评估肿瘤患者放疗期间细胞免疫的变化。