巨细胞病毒血清学阳性的健康女性发生伴有胎儿水肿的严重先天性巨细胞病毒感染。

Severe congenital cytomegalovirus infection with fetal hydrops in a cytomegalovirus-seropositive healthy woman.

作者信息

Inoue T, Matsumura N, Fukuoka M, Sagawa N, Fujii S

机构信息

Department of Gynecology and Obstetrics, Faculty of medicine, Kyoto University, Graduate School of Medicine, Shogoin Kawahara-cho 54, Sakyo-ku, 606-8507, Kyoto, Japan.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2001 Apr;95(2):184-6. doi: 10.1016/s0301-2115(00)00446-2.

DOI:10.1016/s0301-2115(00)00446-2

PMID:11301167

Abstract

We report the case of a woman whose two consecutive pregnancies resulted in intrauterine fetal death due to severe congenital cytomegalovirus infection. In both pregnancies, congenital cytomegalovirus infection was prenatally diagnosed on the basis of detection of cytomegalovirus DNA and specific IgM in cord blood. This case suggests that severe congenital cytomegalovirus infection can occur even in seropositive healthy women.

摘要

我们报告了一例妇女的病例，其连续两次怀孕均因严重先天性巨细胞病毒感染导致宫内胎儿死亡。在这两次怀孕中，先天性巨细胞病毒感染均是基于脐带血中巨细胞病毒DNA和特异性IgM的检测而在产前被诊断出来的。该病例表明，即使是血清学阳性的健康女性也可能发生严重的先天性巨细胞病毒感染。