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J-Express:使用Java探索基因表达数据。

J-Express: exploring gene expression data using Java.

作者信息

Dysvik B, Jonassen I

机构信息

Department of Informatics, University of Bergen, HIB, N5020 Bergen, Norway.

出版信息

Bioinformatics. 2001 Apr;17(4):369-70. doi: 10.1093/bioinformatics/17.4.369.

Abstract

J-Express is a Java application that allows the user to analyze gene expression (microarray) data in a flexible way giving access to multidimensional scaling, clustering, and visualization methods in an integrated manner. Specifically, J-Express includes implementations of hierarchical clustering, k-means, principal component analysis, and self-organizing maps. At present, it does not include methods for comparing two or more experiments for differentially expressed genes. The application is completely portable and requires only that a Java runtime environment 1.2 is installed on the system. Its efficiency allows interactive clustering of thousands of expression profiles on standard personal computers.

摘要

J-Express是一个Java应用程序,它允许用户以灵活的方式分析基因表达(微阵列)数据,以集成的方式提供对多维缩放、聚类和可视化方法的访问。具体来说,J-Express包括层次聚类、k均值、主成分分析和自组织映射的实现。目前,它不包括用于比较两个或多个实验中差异表达基因的方法。该应用程序完全可移植,只要求系统上安装了Java运行时环境1.2。它的效率允许在标准个人计算机上对数千个表达谱进行交互式聚类。

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