Eyal E, Najmanovich R, Sobolev V, Edelman M
Department of Plant Sciences, Weizmann Institute of Science, Rehovot 76100, Israel.
Bioinformatics. 2001 Apr;17(4):381-2. doi: 10.1093/bioinformatics/17.4.381.
A web-based tool, termed 'MutaProt', is described which analyses pairs of PDB files whose members differ in one, or two, amino acids. MutaProt examines the micro environment surrounding the exchanged residue(s) and can be searched by specifying a PDB ID, keywords, or any pair of amino acids. Detailed information about accessibility of the exchanged residue(s) and its atomic contacts are provided based on CSU software (Sobolev et al., Bioinformatics, 15, 327-332, 1999). An interactive 3D presentation of the superimposed regions around the mutation(s) is included. MutaProt is updated weekly.
一种名为“MutaProt”的基于网络的工具被描述，它分析成对的PDB文件，这些文件的成员在一个或两个氨基酸上存在差异。MutaProt会检查被交换残基周围的微观环境，并且可以通过指定PDB ID、关键词或任何一对氨基酸来进行搜索。基于CSU软件（Sobolev等人，《生物信息学》，15卷，327 - 332页，1999年）提供关于被交换残基的可及性及其原子接触的详细信息。还包括围绕突变位点的叠加区域的交互式3D展示。MutaProt每周更新一次。
