Markiewicz A, Wojczuk K, Zmudziński J
Acta Hepatogastroenterol (Stuttg). 1975 Apr;22(2):112-7.
The aim of the study was to ascertain whether the acceleration of physical development in children after operation for coarctation of the aorta is due to the improved intestinal absorption. Lowered values of the oral xylose absorption test were found in all 9 patients before surgery. In all the patients who had been operated on, sphigmo-oscillometry revealed an increased pulsatile character of the blood flow, pulsatile volume in the lower extremities, and a rise of mean arterial blood pressure in this area. On the other hand, surgical repair had no influence on the renal blood flow as evidenced by PAH clearance and isotope renography. There was no correlation of diuresis and the xylose excretion test. Increased values of the xylose test after operation for coarctation of the aorta are due to the increased intestinal absorption rather than to improved renal function. Improved intestinal absorption may be a factor responsible for the accelerated physical development of children operated on for coarctation of the aorta.
本研究的目的是确定主动脉缩窄手术后儿童身体发育加速是否归因于肠道吸收改善。术前所有9例患者的口服木糖吸收试验值均降低。在所有接受手术的患者中,脉搏示波测量显示下肢血流的搏动性特征增强、搏动容量增加以及该区域平均动脉血压升高。另一方面,经对氨基马尿酸清除率和同位素肾图检查证明,手术修复对肾血流量没有影响。利尿与木糖排泄试验之间没有相关性。主动脉缩窄手术后木糖试验值升高是由于肠道吸收增加而非肾功能改善。肠道吸收改善可能是主动脉缩窄手术患儿身体发育加速的一个因素。