Cabral R, Scott D F
Acta Neurol Scand. 1975 May;51(5):380-4. doi: 10.1111/j.1600-0404.1975.tb01377.x.
While alpha rhythm asymmetry among normals is thoroughly documented, the significance of this finding in patients is not well known. The occurrences of alpha amplitude asymmetry in 82 clinical referrals of neuropsychiatric patients was studied in this research. Two separate means of quantifying the alpha asymmetry were used: The first by visual inspection; and the second by measurement in a standard manner. A handedness questionaire was administered and indicated that 77 of the sample were right- and five were left-handed patients. By measurement, the mean overall differences in the alpha amplitude between the hemisphere was small (4 per cent) and non-significant. Seventeen patients showed a difference of 15 per cent or greater, and in two the difference reached 33 per cent. It was concluded that alpha asymmetry must be interpreted with care because it was found that there was an association between left-temporal abnormalities and ipsilateral alpha enhancement, and the greater degrees of asymmetry were found in normal EEGs.
虽然正常人的阿尔法节律不对称现象已有充分记录，但这一发现对患者的意义尚不清楚。本研究对82例神经精神科临床转诊患者的阿尔法波幅不对称情况进行了研究。采用了两种不同的量化阿尔法不对称的方法：第一种是目视检查；第二种是采用标准方式进行测量。发放了一份利手问卷，结果显示样本中有77人是右利手，5人是左利手。通过测量，半球间阿尔法波幅的总体平均差异较小（4%）且无统计学意义。17例患者的差异达到或超过15%，2例患者的差异达到33%。研究得出结论，阿尔法不对称必须谨慎解读，因为发现左侧颞叶异常与同侧阿尔法增强之间存在关联，且在正常脑电图中发现了更大程度的不对称。
