Ormaasen V, Brantsaeter A B, Moen E W
Infeksjonsmedisinsk avdeling Medisinsk divisjon Ullevål sykehus 0407 Oslo.
Tidsskr Nor Laegeforen. 2001 Mar 10;121(7):807-9.
Tick-borne encephalitis is caused by a virus that is transmitted to man by tick-bite. The virus is found in central and eastern parts of Europe and also in Sweden.
We report the first two cases of tick-borne encephalitis resulting from transmission of virus in Norway.
Both patients had been to the island of Tromøy on the south coast of Norway. The course of the disease was very different in the two patients. One patient had significant neurological dysfunction. The other patient had intense headache, but no motor dysfunction. Both patients had reduced general health and fever, and leukocytosis and increased protein was found in the spinal fluid. The incubation period is most often 1 to 2 weeks. The disease may have a bi-phasic course with initial fever, headache and muscle pain. One week later symptoms of encephalitis follow. Subclinical infection is common, especially in children. One third of patients get permanent sequelae after encephalitis. Diagnosis is made by demonstration of antibodies in serum. Treatment is symptomatic.
These two patients indicate that there may be a reservoir of TBE virus in Norway.
蜱传脑炎由一种通过蜱叮咬传播给人类的病毒引起。该病毒在欧洲中部和东部以及瑞典均有发现。
我们报告了挪威首例因病毒传播导致的两例蜱传脑炎病例。
两名患者均去过挪威南海岸的特罗默岛。两名患者的病程差异很大。一名患者有明显的神经功能障碍。另一名患者有剧烈头痛，但无运动功能障碍。两名患者的总体健康状况均下降且发热，脑脊液中发现白细胞增多和蛋白质增加。潜伏期通常为1至2周。该病可能呈双相病程，初期有发热、头痛和肌肉疼痛。一周后出现脑炎症状。亚临床感染很常见，尤其是在儿童中。三分之一的患者在脑炎后会出现永久性后遗症。通过检测血清中的抗体进行诊断。治疗以对症治疗为主。
这两名患者表明挪威可能存在蜱传脑炎病毒的储存宿主。
