卵巢乳头状浆液性腺癌小脑转移酷似梅尼埃病：一例报告

Cerebellar metastasis from papillary serous adenocarcinoma of the ovary mimicking Ménière's disease. A case report.

作者信息

Chang T C, Jain S, Ng K K, Hsueh S, Tsai C S, Chen H L, Chang C N

机构信息

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Change Gung Memorial Hospital Linkou Medical Center and Chang Gung Medical College, Taoyuan, Taiwan.

出版信息

J Reprod Med. 2001 Mar;46(3):267-9.

PMID:11304872

Abstract

BACKGROUND

In rare cases, cerebellar metastasis originating in serous papillary adenocarcinoma of the ovary can mimick Ménière's disease.

CASE

A 51-year-old woman, with complete remission after optimal maximal debulking and chemotherapy for an International Federation of Gynecology and Obstetrics IIIc primary ovarian carcinoma, presented with nausea, vomiting, vertigo and headache 18 months after surgery. Investigations revealed a solitary cerebellar cystic mass, 4.6 x 4.0 x 3.2 cm. Gross total excision of the cerebellar lesion followed by brain irradiation resulted in complete resolution of her symptoms. Histology showed a metastatic tumor consistent with the primary ovarian carcinoma.

CONCLUSION

In an atypical presentation in patients with metastatic ovarian carcinoma, thorough investigations should be done to rule out or confirm brain metastasis, which can be aggressively managed to prevent serious consequences and improve outcome.

摘要

背景

在罕见情况下，起源于卵巢浆液性乳头状腺癌的小脑转移瘤可酷似梅尼埃病。

病例

一名51岁女性，因国际妇产科联盟IIIc期原发性卵巢癌接受了最佳肿瘤细胞减灭术和化疗后达到完全缓解，术后18个月出现恶心、呕吐、眩晕和头痛。检查发现一个孤立的小脑囊性肿块，大小为4.6×4.0×3.2厘米。对小脑病变进行全切除并随后进行脑部放疗后，她的症状完全缓解。组织学检查显示为与原发性卵巢癌一致的转移瘤。