Bioulac B, Lamarre Y
Brain Res. 1979 Aug 31;172(3):427-37. doi: 10.1016/0006-8993(79)90576-6.
Unit recordings were performed in the sensorimotor cortex of awake monkeys during performance of learned movements of the contralateral arm. The movements were triggered by a sound stimulus. The neuronal discharge in association with movement was observed before and after deafferentation (C2--T5) of the operant limb. Whereas neurons recorded in the motor cortex (area 4) and in the parietal association cortex (area 5) still modified their activity in relation to movement performed by the deafferented arm, the neurons recorded in the primary sensory cortex (areas3, 1 and 2) showed no activity change in relation to movement after deafferentation. This finding strongly suggests that modification of discharge of postcentral neurons seen during ballistic arm movement is mainly the result of input from the moving limb (peripheral feedback) and not the result of input from other structures of the central nervous system (internal feedback).
在清醒猴子执行对侧手臂的习得运动期间，对其感觉运动皮层进行单位记录。运动由声音刺激触发。在切断操作肢体的传入神经（C2 - T5）之前和之后，观察到与运动相关的神经元放电。虽然在运动皮层（4区）和顶叶联合皮层（5区）记录到的神经元仍会根据去传入神经手臂执行的运动来改变其活动，但在初级感觉皮层（3、1和2区）记录到的神经元在去传入神经后与运动相关的活动没有变化。这一发现强烈表明，在弹道式手臂运动期间观察到的中央后回神经元放电的改变主要是来自运动肢体的输入（外周反馈）的结果，而不是来自中枢神经系统其他结构的输入（内部反馈）的结果。
