Anderson R C, Anderson T J, Nisbet D J, Kibbe A S, Elrod D, Wilkinson G
United States Department of Agriculture, Southern Plains Agricultural Research Center, College Station, TX 77845, USA.
Vet Hum Toxicol. 2001 Apr;43(2):95-6.
Approximately 80 head of yearling cattle grazing on 680 acres exhibited signs of Leucaena leucocephala toxicosis, which was confirmed in 3 animals by detection of 3-hydroxy-4 (IH)-pyridone, the metabolite of the poisonous principle mimosine, in their urine. The animals had grazed leucaena almost exclusively due to lack of alternative forage resulting from drought conditions. Toxicosis from this otherwise high quality forage would likely not have occurred had animals consumed lower amounts of leucaena and could probably have been prevented, as it has been elsewhere, had the animals been colonized with Synergistes jonesii, a beneficial ruminal bacterium capable of degrading the toxic metabolites.
在680英亩土地上放牧的约80头一岁龄牛出现了银合欢中毒的症状,通过在3只动物尿液中检测到有毒成分含羞草碱的代谢产物3-羟基-4(1H)-吡啶酮,证实了中毒情况。由于干旱条件导致缺乏其他草料,这些动物几乎只食用了银合欢。如果动物食用的银合欢量较少,这种原本优质的草料导致的中毒可能就不会发生,而且如果动物体内定植了琼斯协同菌(一种能够降解有毒代谢产物的有益瘤胃细菌),就像在其他地方那样,中毒情况或许是可以预防的。