Ratliff J L, Hill J D, Fallat R J, Parrot J, Tucker H J
Ann Thorac Surg. 1975 May;19(5):537-9. doi: 10.1016/s0003-4975(10)64429-3.
A series of patients supported with long-term venoarterial perfusion is presented. Gas exchange was achieved with a membrane oxygenator at flows usually in excess of 50% of the patient's baseline cardiac output. Perfusions were maintained for 7 to 12 days. Two major complications were encountered: thromboembolic myocardial infarction and liquefaction necrosis of the lung. Possible etiologies and suggestions for prevention are discussed.
本文介绍了一系列接受长期静脉-动脉灌注支持的患者。使用膜式氧合器实现气体交换,流量通常超过患者基础心输出量的50%。灌注维持7至12天。遇到了两个主要并发症:血栓栓塞性心肌梗死和肺液化坏死。讨论了可能的病因及预防建议。