Serban G, Gidynski C B
Arch Gen Psychiatry. 1975 Jun;32(6):705-12. doi: 10.1001/archpsyc.1975.01760240033002.
Type of onset, presence of precipitating events, mental status, and premorbid instrumental functioning, commonly associated with prognosis in schizophrenia, were studied in relation to the acute-chronic distinction and short-term outcome in 641 schizophrenic patients. Contrary to the general position held by some researchers, none of the clinical predictors (type of onset, precipitating crises, and mental status) appeared to distinguish the two types of schizophrenics, or to contribute substantially to the prediction of readmission. Preadmission social functioning of the two patient groups was more similar than generally indicated by previous reserach. As regards prediction of short-term rehospitalization, the study identified poor relationships with parents, friends, and opposite-sexed peers as important factors for acute patients and antisocial behavior and inability to relate to the opposite sex and others in the community as important variables for chronic patients.
对641名精神分裂症患者，研究了通常与精神分裂症预后相关的起病类型、促发事件的存在、精神状态及病前工具性功能，并将其与急性-慢性区分及短期结局联系起来。与一些研究者的普遍观点相反，没有一个临床预测因素（起病类型、促发危机及精神状态）似乎能区分这两种类型的精神分裂症患者，或对再入院的预测有实质性贡献。两个患者组入院前的社会功能比以往研究所表明的更为相似。关于短期再住院的预测，该研究确定，与父母、朋友及异性同龄人关系不佳是急性患者的重要因素，而反社会行为以及无法与社区中的异性及其他人建立关系是慢性患者的重要变量。
