Brown R L, Leonard T, Saunders L A, Papasouliotis O
Department of Family Medicine, University of Wisconsin-Madsion Medical School, 53715, USA.
J Am Board Fam Pract. 2001 Mar-Apr;14(2):95-106.
Although nonmedical use of illicit and prescription drugs is not uncommon among American adults, the currently recommended screens for substance use disorders focus only on alcohol. This study reports on the criterion validity of a two-item conjoint screen (TICS) for alcohol and other drug abuse or dependence for a split sample of primary care patients.
Two random samples of primary care patients aged 18 to 59 years responded to several screening items that emanated from a focus group process. The DSM-III-R criteria for substance use disorders, as codified by the Composite International Diagnostic Interview-Substance Abuse Module, served as the criterion standard.
At least one positive response to the TICS (In the last year, have you ever drunk or used drugs more than you meant to? and Have you felt you wanted or needed to cut down on your drinking or drug use in the last year?) detected current substance use disorders with nearly 80% sensitivity and specificity. The TICS was particularly sensitive to polysubstance use disorders. Respondents who gave 0, 1, and 2 positive responses had a 7.3%, 36.5%, and 72.4% chance of a current substance use disorder, respectively; likelihood ratios were 0.27, 1.93, and 8.77. The results were consistent across split samples of 434 and 702 participants.
Current alcohol or other drug problems can be detected in nearly 80% of young and middle-aged patients by asking two questions that are easily integrated into a clinical interview.
尽管在美国成年人中非法药物和处方药的非医疗用途并不罕见,但目前推荐的物质使用障碍筛查仅关注酒精。本研究报告了针对初级保健患者的一个分样本,用于筛查酒精及其他药物滥用或依赖的两项联合筛查(TICS)的标准效度。
两组年龄在18至59岁的初级保健患者随机样本,对焦点小组过程中产生的几个筛查项目做出了回应。由综合国际诊断访谈 - 物质滥用模块编纂的《精神疾病诊断与统计手册》第三版修订本(DSM - III - R)中物质使用障碍的标准作为标准参照。
对TICS至少有一个阳性反应(在过去一年中,你是否曾饮酒或使用药物超过你的预期?以及在过去一年中,你是否觉得自己想要或需要减少饮酒或药物使用?)检测当前物质使用障碍的敏感性和特异性接近80%。TICS对多物质使用障碍特别敏感。给出0、1和2个阳性反应的受访者当前患有物质使用障碍的概率分别为7.3%、36.5%和72.4%;似然比分别为0.27、1.93和8.77。在434名和702名参与者的分样本中,结果是一致的。
通过询问两个易于纳入临床访谈的问题,近80%的年轻和中年患者当前的酒精或其他药物问题能够被检测出来。