Glashan R W
Br J Urol. 1975 Feb;47(1):57-66. doi: 10.1111/j.1464-410x.1975.tb03918.x.
30 patients with proven bladder malignant disease have been treated by Helmstein's hydrostatic pressure technique. Massive necrosis of tumour tissue has been shown to occur at cystoscopy, cytologically and on histological examination. Double contrast cystography can indicate reduction in tumour size within 2 weeks of treatment Haematuria is usually stopped with diminution of frequency and dysuria. This treatment is suitable for large bulky T1 tumours and advanced T4 growths where palliation is the only treatment possible but not for TI and T3 growths. Elderly and ill patients can tolerate this therapy easily and there were no serious side-effects in this series.
30例经证实患有膀胱恶性疾病的患者接受了赫尔姆斯坦静水压力技术治疗。膀胱镜检查、细胞学检查和组织学检查均显示肿瘤组织出现大面积坏死。双重对比膀胱造影可显示治疗后2周内肿瘤体积缩小。血尿通常会停止,尿频和排尿困难也会减轻。这种治疗适用于体积较大的T1肿瘤和晚期T4肿瘤,在这些情况下姑息治疗是唯一可行的治疗方法,但不适用于T1和T3肿瘤。老年患者和患病患者能够轻松耐受这种治疗,该系列中未出现严重副作用。