Parker R W, Shaw R E
Br J Surg. 1975 Apr;62(4):298-302. doi: 10.1002/bjs.1800620412.
Thirty-three patients seen in a urological department had taken large doses of analgesic for prolonged periods of time. In 9 cases a diagnosis of pyramidal necrosis was established, while 4 other had pyelographic evidence of pyelonephritis, and analgesic abuse was probably an important aetiological factor in their renal condition. Analgesic nephropathy is easily overlooked unless patients are questioned routinely regarding their intake of analgesic. It is important to identify the group of patients without evidence of serious renal disease who are taking excessive quantities of analgesic and to urge them to abandon the practice.
泌尿科诊治的33例患者长期大量服用镇痛药。其中9例确诊为肾乳头坏死,另有4例肾盂造影显示肾盂肾炎,镇痛药滥用可能是其肾脏疾病的重要病因。除非常规询问患者镇痛药服用情况,否则镇痛药性肾病很容易被忽视。识别出那些服用过量镇痛药但无严重肾脏疾病证据的患者群体,并敦促他们停止这种做法很重要。