Guadagnoli E, Landrum M B, Normand S L, Ayanian J Z, Garg P, Hauptman P J, Ryan T J, McNeil B J
Department of Health Care Policy, Harvard Medical School, Boston MA 02115-5899, USA.
Med Care. 2001 May;39(5):446-58. doi: 10.1097/00005650-200105000-00005.
Geographic variation in the use of medical procedures has been well documented. However, it is not known whether this variation is due to differences in use when procedures are indicated, discretionary, or contraindicated.
To examine whether use of coronary angiography after acute myocardial infarction (AMI) according to appropriateness criteria varied across geographic regions and whether underuse, overuse, or discretionary use accounted for variation in overall use.
Retrospective cohort study using data from the Cooperative Cardiovascular Project.
Ninety-five hospital referral regions.
There were 44,294 Medicare patients hospitalized with AMI during 1994 or 1995, classified according to appropriateness for angiography.
Variation in use of angiography, as measured by the difference between high and low rates of use across regions.
Across regions, variation in the use of angiography was similar for indications judged necessary; appropriate, but not necessary; or uncertain. Variation was lowest for indications judged unsuitable (difference between high rate and low rate across regions = 16.3%; 95% CI = 12.6%; 20.6%). The primary cause of variation in the overall rate of angiography was due to use for indications judged appropriate, but not necessary or uncertain. When variation associated with these indications was accounted for, the difference between the resulting high and low overall rates was 10.8% (9.4%, 12.4%). In contrast, variation in the overall rate remained high when underuse in necessary situations or overuse in unsuitable situations was accounted for.
Across regions, practice was more similar for patients categorized unsuitable for angiography than for patients with other indications. Variation in overall use of angiography appeared to be driven by utilization for discretionary indications rather than by underuse or overuse. If equivalent rates across geographic areas are judged desirable, then greater effort must be directed toward defining care for patients with discretionary indications.
医疗程序使用方面的地域差异已有充分记录。然而,尚不清楚这种差异是由于在有指征、可酌情决定或禁忌使用程序时使用情况的不同所致。
根据适用性标准,研究急性心肌梗死(AMI)后冠状动脉造影的使用在不同地理区域是否存在差异,以及使用不足、过度使用或酌情使用是否是总体使用差异的原因。
利用合作心血管项目的数据进行回顾性队列研究。
95个医院转诊区域。
1994年或1995年期间因AMI住院的44294名医疗保险患者,根据血管造影的适用性进行分类。
血管造影使用情况的差异,通过各区域高低使用率之间的差值来衡量。
在各区域中,对于判断为必要、适当但非必要或不确定的指征,血管造影使用情况的差异相似。对于判断为不适合的指征,差异最小(各区域高使用率与低使用率之间的差值 = 16.3%;95%置信区间 = 12.6%;20.6%)。血管造影总体使用率差异的主要原因是用于判断为适当但非必要或不确定的指征。当考虑与这些指征相关的差异时,由此产生的总体高使用率与低使用率之间的差值为10.8%(9.4%,12.4%)。相比之下,当考虑必要情况下的使用不足或不适合情况下的过度使用时,总体使用率的差异仍然很大。
在各区域中,对于被分类为不适合进行血管造影的患者,其医疗实践比有其他指征的患者更为相似。血管造影总体使用的差异似乎是由酌情使用指征的利用情况驱动的,而非使用不足或过度使用。如果认为各地理区域的使用率相当是可取的,那么必须更加努力地为有酌情使用指征的患者确定治疗方案。