Slaven E M, Lopez F A, Hart S M, Sanders C V
Department of Medicine and Section of Infectious Diseases, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Clin Infect Dis. 2001 May 15;32(10):1430-3. doi: 10.1086/320152. Epub 2001 Apr 17.
Edwardsiella tarda is an unusual human pathogen. It is primarily associated with gastrointestinal disease, although recent reports of extraintestinal disease are broadening the current understanding of the clinical spectrum of E. tarda. A series of 11 cases of extraintestinal E. tarda infection is presented, including the first reported case of myonecrosis in an immunocompetent patient. Wound infections were the most common manifestation, and 3 of 5 patients with infected wounds had been exposed to a marine environment. One patient had bacteremia, and the remaining 5 patients developed abscesses that required surgical drainage. Four patients had E. tarda isolated in pure culture, including the patient with myonecrosis. Although it is often difficult to ascertain the contribution of E. tarda to infection when it is isolated as part of a mixed culture, this case series suggests that E. tarda is singularly capable of causing limb- and life-threatening infections.
迟缓爱德华氏菌是一种不常见的人类病原体。它主要与胃肠道疾病相关，尽管最近有关肠外疾病的报道正在拓宽目前对迟缓爱德华氏菌临床谱的认识。本文报告了11例迟缓爱德华氏菌肠外感染病例，包括首例免疫功能正常患者发生肌坏死的报道。伤口感染是最常见的表现，5例伤口感染患者中有3例曾接触过海洋环境。1例患者发生菌血症，其余5例患者形成了需要手术引流的脓肿。4例患者的培养物中分离出纯培养的迟缓爱德华氏菌，包括发生肌坏死的患者。虽然当迟缓爱德华氏菌作为混合培养的一部分被分离出来时，往往很难确定其对感染的作用，但该病例系列表明，迟缓爱德华氏菌能够单独引起危及肢体和生命的感染。
