Sel'chuk V I, Temnikov A I, Popova T N
N.N. Blokhin Center for Oncology Research, Russian Academy of Medical Sciences, Moscow.
Vopr Onkol. 2001;47(1):90-2.
The data of 100 case histories of primary-multiple synchronous malignancies of the head and neck have been analyzed. A second tumor was not detected during examination of the first one in every third case. The presence of tumor and pain were reported mostly by patients with neoplasms of the tongue, oral mucosa and, less frequently, laryngopharynx. In more than half the cases (48%), head and neck tumors were detected by physical examination. The most frequent were laryngeal tumors (30%), followed by those of the thyroid gland (26%). Second tumor incidence in the lung was (31%), breast (19%) and gastrointestinal tract (18%).