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大豆苷元与大豆苷对铜诱导的蛋白质氧化修饰的抗氧化及螯合作用比较（体外实验）

Comparison of antioxidative and chelating effects of daidzein and daidzin on protein oxidative modification by copper in vitro.

作者信息

Toda S, Shirataki Y

机构信息

Department of Pharmaceutical Science, Kansai College of Oriental Medicine, Sen-nan, Osaka, Japan;

出版信息

Biol Trace Elem Res. 2001 Jan;79(1):83-9. doi: 10.1385/BTER:79:1:83.

DOI:10.1385/BTER:79:1:83
PMID:11318239
Abstract

Daidzein and its glycoside daidzin are isoflavones. Their antioxidative effects were compared in vitro. Although both compounds inhibited protein oxidative modification by copper, the inhibitory effect of daidzein was stronger than that of daidzin. Because daidzein showed a greater affinity for Cu2+, the antioxidant effect of these isoflavones may be dependent on their respective copper-chelating abilities.

摘要

大豆苷元和其糖苷黄豆苷是异黄酮。对它们的抗氧化作用进行了体外比较。虽然这两种化合物都能抑制铜介导的蛋白质氧化修饰，但大豆苷元的抑制作用比黄豆苷更强。由于大豆苷元对Cu2+表现出更高的亲和力，这些异黄酮的抗氧化作用可能取决于它们各自的铜螯合能力。

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