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从俄克拉何马州一只狗身上分离出的一种基因独特的吉氏巴贝斯虫样寄生虫。

A genotypically unique Babesia gibsoni-like parasite recovered from a dog in Oklahoma.

作者信息

Kocan A A, Kjemtrup A, Meinkoth J, Whitworth L C, Murphy G L, Decker L, Lorenz M

机构信息

College of Veterinary Medicine, Oklahoma State University, Stillwater 74078-2006, USA.

出版信息

J Parasitol. 2001 Apr;87(2):437-8. doi: 10.1645/0022-3395(2001)087[0437:AGUBGL]2.0.CO;2.

DOI:10.1645/0022-3395(2001)087[0437:AGUBGL]2.0.CO;2
PMID:11318581
Abstract

A small Babesia gibsoni-like parasite was identified and isolated as the cause of clinical babesiosis in a dog from Oklahoma. Because this was potentially the first documented case of B. gibsoni infection in Oklahoma, further characterization was warranted, and the 18S nuclear small subunit ribosomal RNA gene was sequenced. Sequence comparison with other piroplasms from dogs showed significant nucleotide sequence differences between this isolate and both B. canis and B. gibsoni. These findings demonstrate that in domestic dogs in North America there are at least 2 "small" B. gibsoni-like organisms with distinct nucleotide sequences and that the geographic distribution of the "small" canine Babesia species may be wider than previously recognized.

摘要

在俄克拉荷马州的一只犬中,鉴定并分离出一种小型吉氏巴贝斯虫样寄生虫,它是导致临床巴贝斯虫病的病因。由于这可能是俄克拉荷马州首例有记录的吉氏巴贝斯虫感染病例,因此有必要进一步进行特征描述,并对18S核小亚基核糖体RNA基因进行测序。与犬的其他梨形虫进行序列比较发现,该分离株与犬巴贝斯虫和吉氏巴贝斯虫在核苷酸序列上均存在显著差异。这些发现表明,在北美家犬中,至少存在2种具有不同核苷酸序列的“小型”吉氏巴贝斯虫样生物,并且“小型”犬巴贝斯虫物种的地理分布可能比之前认为的更广。

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Parasit Vectors. 2021 Aug 14;14(1):402. doi: 10.1186/s13071-021-04897-x.
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Development and evaluation of a seminested PCR for detection and differentiation of Babesia gibsoni (Asian genotype) and B. canis DNA in canine blood samples.
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J Clin Microbiol. 2003 Sep;41(9):4172-7. doi: 10.1128/JCM.41.9.4172-4177.2003.