d'Amore A, Massignan C, Montera P, Moles A, De Lorenzo A, Scucchi S
Laboratorio di Alimenti, Istituto Superiore di Sanità, Roma, Italy.
Int J Obes Relat Metab Disord. 2001 Mar;25(3):373-7. doi: 10.1038/sj.ijo.0801565.
To describe some biological, behavioural and psychological correlates of the Three-Factor Eating Questionnaire, and to determine the relationship between dietary restraint, binge eating, and leptin among obese women seeking treatment.
Consecutive series of obese women enrolled in a clinical program for weight reduction treatment.
Forty-two obese women. Eight participants met the criteria for 'severe binge eating' as measured by the Binge Eating Scale.
Energy intake, resting energy expenditure, body composition, leptin, restraint, disinhibition, hunger and binge eating were assessed before starting the treatment.
In this sample both higher disinhibition and hunger scores were associated with greater binge eating severity. Obese women with severe binge eating had lower restraint, higher disinhibition and hunger scores, as well as higher daily fat intake, when compared with obese non-binge-eaters. Interestingly, restraint scores were negatively associated with leptin levels among subjects with severe binge eating.
In obese women with severe binge eating, the negative relationship between dietary restraint and serum leptin concentrations seems mediated by a greater fat intake. These findings need to be verified in further human studies.
描述三因素饮食问卷的一些生物学、行为学和心理学相关因素，并确定寻求治疗的肥胖女性中饮食限制、暴饮暴食和瘦素之间的关系。
连续纳入参加减肥治疗临床项目的肥胖女性系列研究。
42名肥胖女性。8名参与者符合通过暴饮暴食量表测量的“严重暴饮暴食”标准。
在开始治疗前评估能量摄入、静息能量消耗、身体成分、瘦素、饮食限制、去抑制、饥饿感和暴饮暴食情况。
在该样本中，更高的去抑制和饥饿得分与更严重的暴饮暴食程度相关。与非暴饮暴食的肥胖女性相比，患有严重暴饮暴食的肥胖女性饮食限制更低、去抑制和饥饿得分更高，每日脂肪摄入量也更高。有趣的是，在患有严重暴饮暴食症的受试者中，饮食限制得分与瘦素水平呈负相关。
在患有严重暴饮暴食的肥胖女性中，饮食限制与血清瘦素浓度之间的负相关关系似乎是由更高的脂肪摄入量介导的。这些发现需要在进一步的人体研究中得到验证。
