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用于心脏搭桥手术后患者状况自动医疗简报的术中推断的生成与评估。

Generation and evaluation of intraoperative inferences for automated health care briefings on patient status after bypass surgery.

作者信息

Jordan D A, McKeown K R, Concepcion K J, Feiner S K, Hatzivassiloglou V

机构信息

Columbia University, New York, New York 10027, USA.

出版信息

J Am Med Inform Assoc. 2001 May-Jun;8(3):267-80. doi: 10.1136/jamia.2001.0080267.

Abstract

OBJECTIVE

The authors present a system that scans electronic records from cardiac surgery and uses inference rules to identify and classify abnormal events (e.g., hypertension) that may occur during critical surgical points (e.g., start of bypass). This vital information is used as the content of automatically generated briefings designed by MAGIC, a multimedia system that they are developing to brief intensive care unit clinicians on patient status after cardiac surgery. By recognizing patterns in the patient record, inferences concisely summarize detailed patient data.

DESIGN

The authors present the development of inference rules that identify important information about patient status and describe their implementation and an experiment they carried out to validate their correctness. The data for a set of 24 patients were analyzed independently by the system and by 46 physicians.

MEASUREMENTS

The authors measured accuracy, specificity, and sensitivity by comparing system inferences against physician judgments, in cases where all three physicians agreed and against the majority opinion in all cases.

RESULTS

For laboratory inferences, evaluation shows that the system has an average accuracy of 98 percent (full agreement) and 96 percent (majority model). An analysis of interrater agreement, however, showed that physicians do not agree on abnormal hemodynamic events and could not serve as a gold standard for evaluating hemodynamic events. Analysis of discrepancies reveals possibilities for system improvement and causes of physician disagreement.

CONCLUSIONS

This evaluation shows that the laboratory inferences of the system have high accuracy. The lack of agreement among physicians highlights the need for an objective quality-assurance tool for hemodynamic inferences. The system provides such a tool by implementing inferencing procedures established in the literature.

摘要

目的

作者介绍了一种系统,该系统可扫描心脏手术的电子记录,并使用推理规则来识别和分类在关键手术点(如体外循环开始时)可能发生的异常事件(如高血压)。这些重要信息被用作由MAGIC自动生成的简报内容,MAGIC是他们正在开发的一个多媒体系统,用于向重症监护病房的临床医生简要介绍心脏手术后的患者状况。通过识别患者记录中的模式,推理可以简洁地总结详细的患者数据。

设计

作者介绍了识别患者状态重要信息的推理规则的开发过程,并描述了其实施情况以及为验证其正确性而进行的一项实验。该系统和46名医生分别独立分析了一组24名患者的数据。

测量

作者通过将系统推理与医生的判断进行比较来测量准确性、特异性和敏感性,比较的情况包括所有三名医生意见一致的情况以及所有情况下的多数意见。

结果

对于实验室推理,评估表明该系统的平均准确率为98%(完全一致)和96%(多数模型)。然而,对评分者间一致性的分析表明,医生们在异常血流动力学事件上意见不一致,因此不能作为评估血流动力学事件的金标准。对差异的分析揭示了系统改进的可能性以及医生意见不一致的原因。

结论

该评估表明该系统的实验室推理具有很高的准确性。医生之间缺乏一致性凸显了对血流动力学推理进行客观质量保证工具的需求。该系统通过实施文献中确立的推理程序提供了这样一种工具。

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本文引用的文献

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Design of a clinical event monitor.临床事件监测仪的设计
Comput Biomed Res. 1996 Jun;29(3):194-221. doi: 10.1006/cbmr.1996.0016.

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