Kelley G A, Sharpe Kelley K
Department of Kinesiology, Northern Illinois University, DeKalb, USA.
J Gerontol A Biol Sci Med Sci. 2001 May;56(5):M298-303. doi: 10.1093/gerona/56.5.m298.
It is well established that resting systolic and diastolic blood pressure (SBP and DBP, respectively) increases as one ages. This study used the meta-analytic approach to examine the effects of aerobic exercise for reducing resting SBP and DBP in older adults.
Study data were compiled through use of the following: (i) computer searches (MEDLINE, Current Contents, and Sport Discus), (ii) cross-referencing from bibliographies of retrieved studies and review articles, and (iii) an expert who reviewed our reference list. Inclusion criteria and sources for this study were (i) randomized trials, (ii) aerobic activity as the only exercise intervention, (iii) a nonexercise control group, (iv) an assessment of changes in resting SBP and/or DBP, (v) within-study ages of subjects > or = 50 years, (vi) English-language studies published in journals, and (vii) studies published between January 1966 and January 1998. Net changes in resting BP were calculated as the exercise minus control group difference.
Fourteen primary outcomes were derived from seven studies. Decreases of approximately 2% and 1% were found for resting SBP and DBP, with only changes in SBP as statistically significant (SBP, mean +/- SD = -2 +/- 3 mm Hg, 95% confidence interval [CI] = -4 to -1 mm Hg; DBP, mean +/- SD = -1 +/- 2 mm Hg, 95% CI = -2 to 0 mm Hg).
This study supports the efficacy of aerobic exercise for reducing resting SBP in older adults. However, a need exists for studies that address the effectiveness of this intervention for reducing resting BP in older adults.
众所周知，静息收缩压和舒张压（分别为SBP和DBP）会随着年龄的增长而升高。本研究采用荟萃分析方法，探讨有氧运动对降低老年人静息SBP和DBP的影响。
通过以下方式收集研究数据：（i）计算机检索（MEDLINE、《现刊目次》和《体育文献数据库》），（ii）对检索到的研究和综述文章的参考文献进行交叉引用，以及（iii）一位专家审查我们的参考文献列表。本研究的纳入标准和来源为：（i）随机试验，（ii）有氧运动作为唯一的运动干预措施，（iii）非运动对照组，（iv）评估静息SBP和/或DBP的变化，（v）研究对象的年龄在50岁及以上，（vi）发表在期刊上的英文研究，以及（vii）1966年1月至1998年1月期间发表的研究。静息血压的净变化计算为运动组减去对照组的差值。
七项研究得出了14个主要结果。静息SBP和DBP分别下降了约2%和1%，只有SBP的变化具有统计学意义（SBP，均值±标准差=-2±3mmHg，95%置信区间[CI]=-4至-1mmHg；DBP，均值±标准差=-1±2mmHg，95%CI=-2至0mmHg）。
本研究支持有氧运动对降低老年人静息SBP的有效性。然而，需要开展研究以探讨这种干预措施对降低老年人静息血压的效果。
