Kelley G A
Meta-Analytic Research Group, Exercise Science, Department of Physical Education, Northern Illinois University, Dekalb, Illinois, 60115-2854, USA.
Prev Med. 1999 Mar;28(3):264-75. doi: 10.1006/pmed.1998.0417.
The aim of this study was to use the meta-analytic approach to examine the effects of aerobic exercise on resting systolic and diastolic blood pressure among adult women.
Studies were retrieved from computer searches (MEDLINE, Sport Discus, Current Contents) and bibliographies of retrieved articles were cross-referenced. Inclusion criteria were as follows: (1) randomized trials, (2) aerobic activity as the primary exercise intervention, (3) comparative nonexercise control group included, (4) changes in resting systolic and/or diastolic blood pressure assessed for women ages 18 and older, and (5) studies published in English-language journals between January 1966 and January 1998. The primary outcomes retrieved in this study were changes in resting systolic and diastolic blood pressure calculated as the difference (exercise minus control) of the changes (initial minus final) in these mean values.
Ten studies representing 732 subjects and 36 primary outcomes (19 systolic, 17 diastolic) met the criteria for inclusion. Overall, an approximate 2% decrease in resting systolic and 1% decrease in resting diastolic blood pressure were observed (systolic,;x +/- SD = -2 +/- 2.6 mm Hg, 95% bootstrap confidence interval -3 to -1 mm Hg; diastolic,;x +/- SD = -1 +/- 1.9 mm Hg, 95% bootstrap confidence interval -2 to -1 mm Hg).
Aerobic exercise results in small reductions in resting systolic and diastolic blood pressure among adult women. However, a need exists for additional, well-designed studies on this topic, especially among hypertensive adult women.
本研究旨在采用荟萃分析方法,探讨有氧运动对成年女性静息收缩压和舒张压的影响。
通过计算机检索(MEDLINE、Sport Discus、Current Contents)获取研究,并对检索文章的参考文献进行交叉引用。纳入标准如下:(1)随机试验;(2)以有氧运动作为主要运动干预措施;(3)设有非运动对照组;(4)评估18岁及以上女性静息收缩压和/或舒张压的变化;(5)1966年1月至1998年1月期间发表在英文期刊上的研究。本研究获取的主要结果是静息收缩压和舒张压的变化,计算方法为这些平均值变化(初始值减去终末值)的差值(运动组减去对照组)。
10项研究共732名受试者和36个主要结果(19个收缩压,17个舒张压)符合纳入标准。总体而言,观察到静息收缩压约降低2%,静息舒张压约降低1%(收缩压,x±标准差=-2±2.6 mmHg,95%自展置信区间-3至-1 mmHg;舒张压,x±标准差=-1±1.9 mmHg,95%自展置信区间-2至-1 mmHg)。
有氧运动可使成年女性静息收缩压和舒张压略有降低。然而,需要针对该主题开展更多设计良好的研究,尤其是在高血压成年女性中。