Shustin N A
Fiziol Zh SSSR Im I M Sechenova. 1975 Jun;61(6):855-62.
After bilateral ablation of prefrontal and premotor areas of the brain in dogs, considerable changes of the "spontaneous" and unconditioned activity occurred: the phenomenon of squeezing through narrow spaces, the reflex of resistance against restriction of movements, the disturbances of sexual reflexes, the feigned aggression, etc. These reflex actions acquire features of the dominant. Seeking for food, when carrying out instrumental conditioned reflexes, also manifests features of the dominant. The pathological dominant is suggested to be a result of disorder in normal interrelationship between the excitatory and inhibitory processes. It occurs when a disruption of the process of inner inhibition takes place in the system, while the excitatory process becomes extremely powerful. This entails those motor perseverations, hyperactivity, imitational movements, and all the analysed disturbances of reflex activity in dogs after frontal lobectomy.
在对狗的大脑前额叶和运动前区进行双侧切除后，“自发”和非条件活动发生了相当大的变化：出现了挤过狭窄空间的现象、抵抗运动受限的反射、性反射紊乱、假装攻击等。这些反射动作呈现出优势的特征。在进行工具性条件反射时寻找食物，也表现出优势的特征。病理性优势被认为是兴奋和抑制过程之间正常相互关系紊乱的结果。当系统中内抑制过程发生破坏，而兴奋过程变得极其强大时就会出现这种情况。这导致了额叶切除术后狗出现那些运动持续性、多动、模仿动作以及所有分析过的反射活动紊乱。
