Tsakas S, Krimbas C B
Genetics. 1975 Apr;79(4):675-9. doi: 10.1093/genetics/79.4.675.
Three natural populations of Dacus oleae have been sampled for six electrophoretically detected polymorphic genes. The distribution of the allele frequencies in the different populations were analyzed by the method suggested by Lewontin and Krakauer (1973) (the various in space one) in order to test for selective neutrality. This method, however, which in our case showed that one or more genes are or have been subjected to selection, does not permit estimation of the number of selected loci. An improvement of this method is proposed that perimts a minimum estimation of the selected genes. About a third of them seem to be selected in our material. In our case however, where a cytological analysis is not possible, genes are not differentiated from possible inversions including these genes.
对油橄榄实蝇的三个自然种群进行了采样,检测六个经电泳检测的多态基因。采用Lewontin和Krakauer(1973年)建议的方法(空间异质性方法)分析不同种群中等位基因频率的分布,以检验选择中性。然而,在我们的案例中,该方法表明一个或多个基因正在或已经受到选择,但无法估计被选择位点的数量。本文提出了该方法的一种改进方法,可对被选择基因进行最低限度的估计。在我们的材料中,约三分之一的基因似乎受到了选择。然而,在我们的案例中,由于无法进行细胞学分析,基因与包含这些基因的可能倒位无法区分。