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自然种群中电泳变异的单峰性、对称性及阶梯状态假说

Unimodality, symmetry and the step-state hypothesis of electrophoretic variation in natural populations.

作者信息

Haldorson L, King J L

出版信息

J Mol Evol. 1976 Dec 30;8(4):351-6. doi: 10.1007/BF01739260.

Abstract

The population frequency distributions of electromorphs of polymorphic loci, when ordered by electrophoretic mobility, tend strongly and significantly to be both unimodal and symmetrical. Such distributions are predicted by all step-change models and their generality in published data can be construed as supportive of the step-change hypothesis. On the other hand, unimodality and symmetry might also be due to artifactual "unit perception" biases that affect the interpretation and reporting of electrophoretic data. In any case, it appears that perceived electromorphs are highly heterogeneous.

摘要

多态性位点的电变体的群体频率分布,按电泳迁移率排序时,往往强烈且显著地呈单峰且对称。所有阶跃变化模型都预测了这种分布,并且它们在已发表数据中的普遍性可被视为支持阶跃变化假说。另一方面,单峰性和对称性也可能是由于影响电泳数据解释和报告的人为“单位感知”偏差。无论如何,似乎所感知到的电变体具有高度的异质性。

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