Colding-Jørgensen E, Vissing J
Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Acta Neurol Scand. 2001 Apr;103(4):259-60.
Autoimmune neuropathies such as the Guillain-Barré syndrome (GBS), the Miller Fisher syndrome (MFS), and chronic inflammatory demyelinating neuropathy (CIDP) have conventionally been considered diseases exclusively of the peripheral nervous system. In the last decades, however, several reports of CNS involvement in peripheral neuropathy have challenged this view. We describe a patient with anti-GQ1b positive MFS who--apart from the classical features--also presented with reversible loss of visual acuity suggesting CNS involvement.
自身免疫性神经病,如吉兰-巴雷综合征(GBS)、米勒-费雪综合征(MFS)和慢性炎症性脱髓鞘性多发性神经病(CIDP),传统上被认为是仅累及周围神经系统的疾病。然而,在过去几十年中,几篇关于中枢神经系统(CNS)受累于周围神经病的报道对这一观点提出了挑战。我们描述了一名抗GQ1b阳性的MFS患者,该患者除了具有典型特征外,还出现了提示中枢神经系统受累的视力可逆性丧失。