Kolokol'chikova E G, Budkevich L I, Bobrovnikov A E, Badikova A K, Tumanov V P
Department of Pathological Anatomy, A. V. Vishnevskii Institute of Surgery, Russian Academy of Medical Sciences, Moscow.
Bull Exp Biol Med. 2001 Jan;131(1):89-93. doi: 10.1023/a:1017503301550.
Cultured allogenic fibroblasts labeled with fluorescent acridine orange and transplanted onto burn wound virtually completely disappear from the wound surface within 2 days (are destroyed). Study of wound morphology by light autoradiography and quantitative analysis showed a stimulating effect of transplanted fibroblasts on wound healing. This effect, irrespective of the initial state of the wound, is always directed at accelerated formation of connective tissue similar to the derma and capable of epithelialization.
用荧光吖啶橙标记的同种异体培养成纤维细胞移植到烧伤创面后，实际上在2天内就从创面完全消失（被破坏）。通过光放射自显影术对创面形态进行研究并进行定量分析表明，移植的成纤维细胞对创面愈合有促进作用。这种作用与创面的初始状态无关，总是朝着加速形成类似于真皮且能够进行上皮化的结缔组织的方向发展。
