Mattsson C M, Mårild S, Pehrsson N G
Central Unit for Child Health Care, South Bohuslän, Västra Götaland, Sweden.
Acta Paediatr. 2001 Mar;90(3):339-44.
A population-based language-screening programme started in the western part of Sweden (South Bohuslän) in 1991, with the aim of identifying developmental language disability in 2.5-y-old children. The programme was evaluated during 1998 in an experimental study. A group of 105 2.5-y-old children was recruited from 24 separate Child Health Centres. A sample of 25 children with a positive screening result was selected. For each of the 25 children, 1-4 controls, i.e. children with a negative screening result, were selected. The results were reclassified blindly by three speech and language therapists and used as a gold standard. Positive and negative predictive values were estimated to be 0.52 (95% confidence interval 0.31-0.72) and 0.96 (95% confidence interval 0.89-0.99), respectively. Baye's theorem was used to calculate the sensitivity (0.69) and the specificity (0.93) of the screening. A method of calculating the sensitivity and specificity of the test method by means of three samples was demonstrated.
The data confirm that it is possible to identify reliably children with developmental language disability at 2.5 y of age through the screening programme.
1991年在瑞典西部(南博胡斯兰)启动了一项基于人群的语言筛查项目,目的是识别2.5岁儿童的发育性语言障碍。1998年在一项实验研究中对该项目进行了评估。从24个独立的儿童健康中心招募了105名2.5岁儿童。选取了25名筛查结果呈阳性的儿童作为样本。对于这25名儿童中的每一名,选取1 - 4名对照,即筛查结果呈阴性的儿童。结果由三名言语和语言治疗师进行盲法重新分类,并用作金标准。阳性预测值和阴性预测值估计分别为0.52(95%置信区间0.31 - 0.72)和0.96(95%置信区间0.89 - 0.99)。使用贝叶斯定理计算筛查的敏感性(0.69)和特异性(0.93)。展示了一种通过三个样本计算测试方法敏感性和特异性的方法。
数据证实通过筛查项目能够可靠地识别2.5岁患有发育性语言障碍的儿童。